Clinical studies of hydroxycitric acid weight loss supplements indicate there are minimal immediate side effects to taking 1500 mg of hydroxycitric acid per day when compared to subjects administered a placebo. However, hydroxycitric acid supplements may cause gastrointestinal discomfort, headaches and upper respiratory tract problems, such as coughing or wheezing.
Acute Skin ExposureStudies on laboratory animals indicate that long-term direct exposure to high levels of hydroxycitric acid to the skin may cause irritation and yellowing of the affected area. However, these studies were conducted with concentrations of hydroxycitric acid many times greater than found in food supplements, and the studies indicate the chemical would not likely cause skin irritation for healthy people.
Eye ExposureAlthough there is no evidence that ingesting hydroxycitric acid causes eye irritation, it can cause inflammation and a burning sensation if put directly into the eye. Laboratory studies indicate that when the eye is exposed to hydroxycitric acid it can cause inflammation and reddening for several weeks if left untreated. However, there was no indication that it caused any permanent damage to the eye.
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