Suggested Use: As an herbal dietary supplement, take one morinda capsule 1 or 2 times daily.
buy Morinda Citrifolia supplement
Chemistry
Morinda citrifolia has been documented to contain a mixture of anthraquinones, organic acids, xeronine, several vitamins (such as beta-carotene, niacin, riboflavin, thiamine), some minerals, iron and calcium. The potassium content is similar to that in tomato juice and orange juice.
Morinda Citrifolia supplement uses - benefit of juice or extract
Claims have been made that juice or extract improves the immune system, ultimately healing dozens of conditions ranging from addictions to varicose veins and yeast rash. What does the scientific research say about the benefit of Morinda citrifolia juice and extract supplement?
Cancer protection
Antitumour potential of a polysaccharide-rich substance from the fruit juice of Morinda citrifolia on sarcoma 180 ascites tumour in mice.
Phytother Res. 2003.
An immunomodulatory polysaccharide-rich substance (Noni-ppt) from the fruit juice of Morinda citrifolia has been found to possess both prophylactic and therapeutic potentials against the immunomodulator sensitive Sarcoma 180 tumour system. The antitumour activity of Morinda citrifolia produced a cure rate of 25%-45% in allogeneic mice and its activity was completely abolished by the concomitant administration of specific inhibitors of macrophages (2-chloroadenosine), T cells (cyclosporine) or natural killer (NK) cells (anti-asialo GM1 antibody). Morinda citrifolia showed synergistic or additive beneficial effects when combined with a broad spectrum of chemotherapeutic drugs, including cisplatin, adriamycin, mitomycin-C, bleomycin, etoposide, 5- fl uorouracil, vincristine or camptothecin. It was not beneficial when combined with paclitaxel, cytosine arabinoside, or immunosuppressive anticancer drugs such as cyclophosphamide, methotrexate or 6-thioguanine. Morinda citrifolia also demonstrated beneficial effects when combined with the Th1 cytokine, interferon gamma, but its activity was abolished when combined with Th2 cytokines, interleukin-4 or interleukin-10, thereby suggesting that Morinda citrifolia induces a Th1 dominant immune status in vivo. The combination of Morinda citrifolia with imexon, a synthetic immunomodulator, also demonstrated beneficial effects, but not when combined with the MVE-2 copolymer, a high molecular weight immunomodulator. Morinda citrifolia was also not effective when combined with interleukin-2 or interleukin-12.
Asian Pac J Cancer Prev. 2013. Morinda citrifolia (Noni) alters oxidative stress marker and antioxidant activity in cervical cancer cell lines. A decrease in level of lipid peroxidation and an increase in catalase activity were observed with Noni by itself and the effect ameliorated changes observed with cisplatin when given in combination.
Morinda Citrifolia and cholesterol
Reductions in total cholesterol and triglycerides have been seen in smokers who drank a product containing juice from the fruit of the Morinda citrifolia tree every day for a month. The study was funded by the manufacturer of the product, sold as Tahitian Noni Juice. Researcher Mian-Ying Wang, MD, says she first became interested in studying Morinda citrifolia juice in 1999 after becoming convinced that it helped reduce her pain from a wrist fracture.
Morinda Citrifolia and diabetes
In Java, Morinda citrifolia has been part of the treatment for diabetes. Most of the folk uses for diabetes involve chewing the leaves or a combination of the plant and leaves. Chewing mulberry leaves releases and activates large amounts of mucilage or insoluble dietary fiber. The fiber may slow the absorption of simple sugars from the gut. The effect in most patients would be a slight reduction in the peak glucose level following a meal.
Infections prevention and treatment
Infections are the most common applications of Morinda species. The extract from the leaves of Morinda citrifolia (not the fruit that renders noni juice) displayed a moderate suppression of Ascaris lumbricoides (intestinal nematodes) growth in the test tube. However, Morinda citrifolia juice has not been shown to improve infections once symptoms have manifested, although there are anecdotal reports of patients feeling better from mild infections after using noni. Decoctions of the leaves or roots of related mulberry species may have some suppressive effect on parasitic infections.
J Agric Food Chem. 2014 Feb 14. The Anti-adhesion and Anti-inflammation of Morinda citrifolia Fruit extracts on AGS cells During Helicobacter pylori Infection. Helicobacter pylori (H. pylori) is a human gastric pathogen, which adheres to host cell and injects cytotoxin-associated gene A (CagA) to induce interleukin-8 (IL-8), inducible nitric oxide (iNOS) and cyclooxygenase 2 (COX-2). Noni (Morinda citrifolia) is found to possess anti-bacteria, anti-inflammation and anti-oxidation, but its effect on H. pylori infection is still unknown. Ethanol and ethyl acetate extracts of noni fruit were used in this study. The inhibitory effect on CagA and H. pylori-induced IL-8, iNOS and COX-2 were determined. The co-culture medium was collected for measuring neutrophil chemotaxis. Both extracts of noni fruit showed weak inhibition on H. pylori. Both ethanol and ethyl acetate extracts provided anti-adhesion of H. pylori to AGS cells and down-regulation on the CagA, IL-8, COX-2 and iNOS expression. Results also indicated both extracts relieved neutrophil chemotaxis. Noni fruit extracts down-regulated inflammatory responses during H.pylori infection, and the phenolic compounds play key role on anti-adhesion.
Pain
Pain, painful inflammation and swellings are the second most common usage of Morinda species. Studies in mice have demonstrated that extracts from the root of Morinda citrifolia (again, not rendered from the fruit) have some pain relieving and sedative activity.
Side effects of m orinda citrifolia
In some regions of the world Morinda citrifolia and other mulberry species are used as a laxative. Predictably, some patients using higher concentrations of Morinda citrifolia juice may experience some diarrhea. Although the risk of long-term adverse reactions is not currently known, it should be very low, because of the long history of mulberry species as a food in wide geographic regions. Patients with diabetes would be wise to find out the amount of sugars used to sweeten the particular product they wish to use.
There have been two reported cases in the medical literature regarding liver damage due to excessive morinda citrifolia juice consumption. As with any herb, it is best to use low amounts. I prefer using small amounts of different herbs as opposed to a large amount of a single herb.
Morinda Citrifolia dosage
Suggested dose is three capsules per day, taken with a few ounces of water, half an hour before a meal. All three capsules may be taken at once or in divided doses. Three capsules are equivalent to about two tablespoons of liquid Morinda citrifolia juice. A concentrated form of the juice is also available. Morinda citrifolia is often mixed with other fruit juices because of its unpleasant taste.
Conclusion
At this point, there is no firm scientific data to support the use of Morinda citrifolia juice as a substitute for any standard medical treatment. Patients who are looking for additional help in treating mild infections, cancer or chronic pain could try Morinda citrifolia , realizing that the benefits are not predictable. Perhaps future research will give us additional clues to the potential therapeutic benefits of using Morinda citrifolia juice or extracts. In the meantime, due to its content of various nutrients, Morinda citrifolia juice is a healthy drink to consume as part of an overall balanced diet, as long as you drink no more than one ounce every other day.
Inhibition of angiogenic initiation and disruption of newly established human vascular networks by juice from Morinda citrifolia.
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