Maintaining Optimal Vitamin D Status
According to the NIH, blood serum concentration of 25-hydroxyvitamin D (25(OH)D) is the best indicator of a person's vitamin D status. Blood levels of 25(OH)D are measured in nanomoles per liter (nmol/L). Concentrations of 37.5 nmol/L are considered adequate by the National Institute of Medicine (NIM), although some research, including a 2008 study by the Bone Mineral Research Center, cites evidence that optimal 25(OH)D concentration is at least 75 nmol/L. This study concluded that daily vitamin D3 dosage of 3800 to 5000 IU is necessary to achieve 25(OH)D concentration of 75nmol/L. A 2003 study, which considered 70.3 nmol/L the optimal concentration, concluded that healthy men require at least 3000 to 5000 IU of vitamin D3 daily during winter months. Older adults may also benefit from vitamin D3 dosing of 5000 IU. A 2010 study conducted by the University of Saskatchewan concluded that while adults under than the age of 65 need at least 2000 IU daily to maintain 25(OH)D concentration of 75nmol/L, those 65 and older need at least 5000 IU.
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